SIGLEC-5,SIGLEC-14 antibody (FITC)

Details for Product No. ABIN2476480
Antigen
  • SIGLEC5
  • sialic acid binding Ig like lectin 14
  • SIGLEC14
Reactivity
Chimpanzee, Human
11
5
Host
Mouse
8
3
Clonality (Clone)
Monoclonal ()
Conjugate
FITC
2
2
Application
Flow Cytometry (FACS)
8
7
5
5
3
3
1
1
Options
Immunogen Siglec-5-Fc protein, consisting of the full-length extracellular region of human Siglec-5, fused with the Fc region of human IgG1.
Clone 1A5
Isotype IgG1
Cross-Reactivity Chimpanzee
Characteristics Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC)
Antigen
Alternative Name Siglec-5/Siglec-14
Gene ID 8778, 100049587
UniProt O15389, Q08ET2
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.1 mg/mL
Product cited in: Nguyen, Hurtado-Ziola, Gagneux, Varki: "Loss of Siglec expression on T lymphocytes during human evolution." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 20, pp. 7765-70, 2006 (PubMed).

Avril, Freeman, Attrill, Clarke, Crocker: "Siglec-5 (CD170) can mediate inhibitory signaling in the absence of immunoreceptor tyrosine-based inhibitory motif phosphorylation." in: The Journal of biological chemistry, Vol. 280, Issue 20, pp. 19843-51, 2005 (PubMed).

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