HAVCR1 antibody (PE)

Catalog No. ABIN2476813

This Rat Monoclonal antibody specifically detects HAVCR1 in FACS. It exhibits reactivity toward Mouse. It has been mentioned in 3+ publications

Quick Overview for HAVCR1 antibody (PE) (ABIN2476813)

Target: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This HAVCR1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: RMT1-10

Product Details anti-HAVCR1 Antibody (PE)

Characteristics: Purified IgG conjugated to R. Phycoerythrin (RPE)

Immunogen: Full-length mouse Tim-1-Ig, containing both the IgV and mucin domains of Tim-1.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

References for anti-HAVCR1 antibody (PE) (ABIN2476813)

Freeman, Casasnovas, Umetsu, DeKruyff: "TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity." in: Immunological reviews, Vol. 235, Issue 1, pp. 172-89, (2010) (PubMed).

Yuan, Ansari, DAddio, Paez-Cortez, Schmitt, Donnarumma, Boenisch, Zhao, Popoola, Clarkson, Yagita, Akiba, Freeman, Iacomini, Turka, Glimcher, Sayegh: "Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 26, pp. 10734-9, (2009) (PubMed).

Xiao, Najafian, Reddy, Albin, Zhu, Jensen, Imitola, Korn, Anderson, Zhang, Gutierrez, Moll, Sobel, Umetsu, Yagita, Akiba, Strom, Sayegh, DeKruyff, Khoury, Kuchroo: "Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function." in: The Journal of experimental medicine, Vol. 204, Issue 7, pp. 1691-702, (2007) (PubMed).

Target Details for HAVCR1

Target: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Alternative Name: TIM-1

Target Type: Virus

Background: Synonyms: T-CELL IMMUNOGLOBULIN MUCIN 1

Gene ID: 171283

UniProt: Q5QNS5