HTR7 antibody (C-Term)

Catalog No. ABIN2477210

The Rabbit Polyclonal anti-HTR7 antibody has been validated for IHC (p). It is suitable to detect HTR7 in samples from Human and Mouse. There are 2+ publications available.

Quick Overview for HTR7 antibody (C-Term) (ABIN2477210)

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR7 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HTR7 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Mouse (Murine)

Characteristics: Purified IgG

Purification: Purified

Immunogen: Synthetic peptide C-terminal regoin of human 5-HT7 receptor, conjugated to Keyhole Limpet Hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-HTR7 antibody (ABIN2477210)

Kobe, Guseva, Jensen, Wirth, Renner, Hess, Müller, Medrihan, Zhang, Zhang, Braun, Westerholz, Herzog, Radyushkin, El-Kordi, Ehrenreich, Richter, Rusakov, Ponimaskin: "5-HT7R/G12 signaling regulates neuronal morphology and function in an age-dependent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 9, pp. 2915-30, (2012) (PubMed).

León-Ponte, Ahern, OConnell: "Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor." in: Blood, Vol. 109, Issue 8, pp. 3139-46, (2007) (PubMed).

Target Details for HTR7

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Alternative Name: 5-HT7 RECEPTOR

Background: Synonyms: HTR7

Gene ID: 3363

UniProt: P34969

Pathways: JAK-STAT Signaling