CD200 antibody

Catalog No. ABIN2479108

Product Details anti-CD200 Antibody

Target: CD200

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD200 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purpose: MOUSE ANTI HUMAN CD200

Characteristics: Mouse anti Human CD200 antibody, clone OX-104 recognizes the human CD200 cell surface antigen, also known as OX2.CD200 is expressed by a subset of B lymphocytes, some endothelial cells and by neurons. The CD200-CD200 ligand system is of importance in the control of macrophage and granulocyte activation.

Purification: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant

Clone: OX-104

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline,0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment: This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

References for anti-CD200 antibody (ABIN2479108)

Koning, Swaab, Hoek, Huitinga: "Distribution of the immune inhibitory molecules CD200 and CD200R in the normal central nervous system and multiple sclerosis lesions suggests neuron-glia and glia-glia interactions." in: Journal of neuropathology and experimental neurology, Vol. 68, Issue 2, pp. 159-67, (2009) (PubMed).

Ko, Chien, Jiang-Shieh, Chang, Pai, Huang, Chen, Wu: "Endothelial CD200 is heterogeneously distributed, regulated and involved in immune cell-endothelium interactions." in: Journal of anatomy, Vol. 214, Issue 1, pp. 183-95, (2009) (PubMed).

Wright, Jones, Puklavec, Brown, Barclay: "The unusual distribution of the neuronal/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans." in: Immunology, Vol. 102, Issue 2, pp. 173-9, (2001) (PubMed).

Target Details for CD200

Target: CD200

Alternative Name: CD200 (CD200 Products)

Background: Synonyms: OX2

Gene ID: 4345

UniProt: P41217