LAG3 antibody

Catalog No. ABIN2479314

This Rat Monoclonal antibody specifically detects LAG3 in FACS. It exhibits reactivity toward Mouse and has been mentioned in 3+ publications.

Quick Overview for LAG3 antibody (ABIN2479314)

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This LAG3 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: C9B7W

Product Details anti-LAG3 Antibody

Characteristics: Purified IgG

Purification: Purified

Immunogen: Murine CD223 Ig fusion protein

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-LAG3 antibody (ABIN2479314)

Byrne, Côté, Zhang, Steinberg, Guo, Allie, Zhang, Ernstoff, Usherwood, Turk: "Autoimmune melanocyte destruction is required for robust CD8+ memory T cell responses to mouse melanoma." in: The Journal of clinical investigation, Vol. 121, Issue 5, pp. 1797-809, (2011) (PubMed).

Workman, Vignali: "Negative regulation of T cell homeostasis by lymphocyte activation gene-3 (CD223)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 2, pp. 688-95, (2005) (PubMed).

Workman, Rice, Dugger, Kurschner, Vignali: "Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3)." in: European journal of immunology, Vol. 32, Issue 8, pp. 2255-63, (2002) (PubMed).

Target Details for LAG3

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Alternative Name: CD223

Background: Synonyms: LAG-3

Gene ID: 16768

UniProt: Q61790

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints