CACNA1D antibody (AA 859-875) (Atto 488)

Catalog No. ABIN2484057

This Mouse Monoclonal antibody specifically detects CACNA1D in IHC, WB, IP, ICC, IF and AA. It exhibits reactivity toward Rat.

Quick Overview for CACNA1D antibody (AA 859-875) (Atto 488) (ABIN2484057)

Target: CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CACNA1D antibody is conjugated to Atto 488

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Antibody Array (AA)

Clone: S48

Product Details anti-CACNA1D Antibody (Atto 488)

Binding Specificity: AA 859-875

Specificity: Detects ~250 kDa. No cross-reactivity against Cav1.2.

Cross-Reactivity: Human, Mouse, Rat

Purification: Protein G Purified

Immunogen: Fusion protein amino acids 859-875 of rat Cav1.3

Isotype: IgG2a kappa

Application Details

Application Notes:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Comment:

1 μg/ml of ABIN2484057 was sufficient for detection of Cav1.3 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Conjugated antibodies should be stored at 4°C

Target Details for CACNA1D

Target: CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))

Alternative Name: Cav1.3

Background: CaV1.3, also known as the calcium channel, voltage-dependent, L type, alpha 1D subunit (CACNA1D), is a human gene. CaV1.3 subunits are primarily expressed in neurons and neuroendocine cells. Some studies suggest however that CaV1.3 is also found in the atria, and may figure prominently in atrial arrhythmias (1). CaV1.3 also carries the primary sensory receptors of the mammalian cochlea, and are also expressed in the electromotile outer hair cells (2).

Gene ID: 29716

NCBI Accession: NP_058994

UniProt: P27732

Pathways: Sensory Perception of Sound