Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 (SLC18A3) (AA 521-532) antibody (APC)

Catalog No. ABIN2485326

Product Details

Target:

Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 (SLC18A3)

Binding Specificity: AA 521-532

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: APC

Application: Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)

Specificity: Detects ~56 kDa.

Purification: Protein G Purified

Immunogen: Synthetic peptide amino acids 521-532 of human VAChT

Clone: S6-38

Isotype: IgG1

Application Details

Application Notes:

• WB (1:1000)
• IHC (1:200)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Comment:

A dilution of 1:50-1:200 of SMC-341 was sufficient for detection of VAChT Transporter in rat brain using immunohistochemistry analysis and goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details

Target:

Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 (SLC18A3)

Alternative Name: VAChT (SLC18A3 Antibody Abstract)

Synonyms: CG12345, CG32848, CT41182, Dmel\\CG32848, VACHT, VACht, Vacht, vAChT, vacht, SLC18A3, rVAT, Slc18a3, MGC64220, VAChT, VAT, Vesicular acetylcholine transporter, solute carrier family 18 member A3, solute carrier family 18 (vesicular acetylcholine transporter), member 3, solute carrier family 18 (vesicular acetylcholine transporter), member 3b, solute carrier family 18 (vesicular monoamine), member 3, VAChT, SLC18A3, slc18a3, Slc18a3, slc18a3b

Background: VAChT is a member of the vesicular amine transporter (VMAT) family. The encoded transmembrane protein transports acetylcholine into secretory vesicle for release into the extracellular space. Acetylcholine (Ach) transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.

Gene ID: 6572

NCBI Accession: NP_003046

UniProt: Q16572