SLC18A3 antibody (AA 521-532) (Biotin)

Catalog No. ABIN2485327

Product Details anti-SLC18A3 Antibody (Biotin)

Target: SLC18A3 (Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 (SLC18A3))

Binding Specificity: AA 521-532

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLC18A3 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Detects ~56 kDa.

Cross-Reactivity: Human, Mouse, Rat

Purification: Protein G Purified

Immunogen: Synthetic peptide amino acids 521-532 of human VAChT

Clone: S6-38

Isotype: IgG1

Application Details

Application Notes:

• WB (1:1000)
• IHC (1:200)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Comment:

A dilution of 1:50-1:200 of SMC-341 was sufficient for detection of VAChT Transporter in rat brain using immunohistochemistry analysis and goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Conjugated antibodies should be stored at 4°C

Target Details for SLC18A3

Target: SLC18A3 (Solute Carrier Family 18 (Vesicular Acetylcholine), Member 3 (SLC18A3))

Alternative Name: VAChT (SLC18A3 Products)

Background: VAChT is a member of the vesicular amine transporter (VMAT) family. The encoded transmembrane protein transports acetylcholine into secretory vesicle for release into the extracellular space. Acetylcholine (Ach) transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.

Gene ID: 6572

NCBI Accession: NP_003046

UniProt: Q16572