NPAS4 antibody (AA 597-802) (PerCP)

Catalog No. ABIN2485821

This Mouse Monoclonal antibody specifically detects NPAS4 in WB, IHC, IF and ICC. It exhibits reactivity toward Rat.

Quick Overview for NPAS4 antibody (AA 597-802) (PerCP) (ABIN2485821)

Target: NPAS4 (Neuronal PAS Domain Protein 4 (NPAS4))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This NPAS4 antibody is conjugated to PerCP

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: S408-79

Product Details anti-NPAS4 Antibody (PerCP)

Binding Specificity: AA 597-802

Specificity: Highly expressed in the brain, with lower expression found in endocrine tissue.,Detects ~90 kDa.

Cross-Reactivity: Human, Mouse, Rat

Purification: Protein G Purified

Immunogen: Fusion protein amino acids 597-802 (C-terminus) of rat Npas4.

Isotype: IgG1

Application Details

Application Notes:

• WB (1:1000)
• ICC/IF(1:100)
• optimal dilutions for assays should be determined by the user.

Comment:

A 1:100 dilution of ABIN2485821 was sufficient for detection of NPAS4 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Conjugated antibodies should be stored at 4°C

Target Details for NPAS4

Target: NPAS4 (Neuronal PAS Domain Protein 4 (NPAS4))

Alternative Name: NPAS4

Background: NPAS4 belongs to the Per-Arnt-Sim family of neuronal specific transciption factors, all involved in the development and maintenance of learning and memory pathways (1). NPAS4 is a transcription factor that regulates the formation and maintenance of inhibitory synapses, and can activate the CNS midline enhancer element and the expression of the drebrin gene. Deregulation has been to be associated with developmental disorders such as schizophrenia and autism (2).

Gene ID: 266734

NCBI Accession: NP_705890

UniProt: Q8CJH6