REPS2 antibody (C-Term)

Catalog No. ABIN2499755

This Rabbit Polyclonal antibody specifically detects REPS2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Pig.

Quick Overview for REPS2 antibody (C-Term) (ABIN2499755)

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REPS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-REPS2 Antibody

Binding Specificity: C-Term

Sequence: KDVLYSQPPS KPIRRKFRPE NQATENQEPS TAASGPASAA TMKPHPTVQK

Predicted Reactivity: Cow: 100%, Dog: 80%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 83%, Pig: 100%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against REPS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human REPS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for REPS2

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Alternative Name: REPS2

Background: The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: EPN1, CDK1, AP2A1, GRB2, AMPH, AR, CDK5RAP2, REPS1, RALBP1, EPS15, ASAP1, ASAP2, PXN, RALB, RELA,
Protein Size: 521

Molecular Weight: 57 kDa

Gene ID: 9185

Pathways: EGFR Signaling Pathway