REPS2 antibody (AA 390-470)

Catalog No. ABIN7230998

This Rabbit Polyclonal antibody specifically detects REPS2 in WB and ELISA. It exhibits reactivity toward Mouse and Human.

Quick Overview for REPS2 antibody (AA 390-470) (ABIN7230998)

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REPS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-REPS2 Antibody

Binding Specificity: AA 390-470

Purpose: Rabbit Anti-REPS2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of REPS2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human REPS2 protein at AA range: 390-470

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for REPS2

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Alternative Name: REPS2

Background: RalBP1-associated Eps domain-containing protein 2, Partner of RalBP1, RalBP1-interacting protein 2The product of REPS2 (RALBP1 Associated Eps Domain Containing 2) is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for REPS2.

Molecular Weight: 72kD

Gene ID: 9185

UniProt: Q8NFH8

Pathways: EGFR Signaling Pathway