IL7R antibody (PE-Cy5)

Catalog No. ABIN2567211

The Mouse Monoclonal anti-IL7R antibody has been validated for FACS. It is suitable to detect IL7R in samples from Human.

Quick Overview for IL7R antibody (PE-Cy5) (ABIN2567211)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL7R antibody is conjugated to PE-Cy5

Application: Flow Cytometry (FACS)

Clone: RDR5

Product Details anti-IL7R Antibody (PE-Cy5)

Specificity: The RDR5 monoclonal antibody specifically reacts with human CD127, a 60-90 kDA type I transmembrane glycoprotein also known as the IL-7 receptor alpha chain.

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Storage: 4 °C

Storage Comment: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Target Details for IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Alternative Name: CD127

Background: The RDR5 monoclonal antibody specifically reacts with human CD127, a 60-90 kDA type I transmembrane glycoprotein also known as the IL-7 receptor alpha chain. CD127 binds with CD132 (gamma c) to forms the IL-7 receptor that is expressed on mature T cells and immature B cells. Since CD127 expression is downregulated in Treg cells, it can be used as a marker for differentiating them from common T cells. The binding of the RDR5 antibody can be blocked by pre-incubating the cells with human IL-7.

Gene ID: 3575

UniProt: P16871

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size