BTLA antibody (Biotin)

Catalog No. ABIN2567404

The Biotin-conjugated Mouse Monoclonal anti-BTLA antibody (Clone MIH26) (ABIN2567404) specifically detects BTLA in FACS. The antibody is reactive with Human samples.

Quick Overview for BTLA antibody (Biotin) (ABIN2567404)

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BTLA antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: MIH26

Product Details anti-BTLA Antibody (Biotin)

Specificity: The MIH26 monoclonal antibody specifically reacts with human CD272, the human and B and T lymphocyte attenuator (BTLA).

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Storage: 4 °C

Storage Comment: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Target Details for BTLA

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Alternative Name: CD272

Background: The MIH26 monoclonal antibody specifically reacts with human CD272, the human and B and T lymphocyte attenuator (BTLA). It is expressed on macrophage, dendritic, NK, NKT, B, and T cells. CD272 (BTLA) is an inhibitory receptor that inhibits T cell proliferation after binding with its ligand, the herpes virus entry mediator (HVEM). It is in the CD28-like family of receptors and is structurally similar to CTLA-4 and PD-1.

Gene ID: 151888

UniProt: Q7Z6A9

Pathways: Cancer Immune Checkpoints