CD51/CD61 antibody

Catalog No. ABIN2567844

The Mouse Monoclonal anti-CD51/CD61 antibody has been validated for FACS and Func. It is suitable to detect CD51/CD61 in samples from Human.

Quick Overview for CD51/CD61 antibody (ABIN2567844)

Target: CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD51/CD61 antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: 23C6

Product Details anti-CD51/CD61 Antibody

Specificity: The 23C6 monoclonal antibody specifically reacts with the human CD51/61 Molecule, known as the integrin alpha v Beta 3 complex or vitronectin receptor.

Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Storage: 4 °C

Storage Comment: The product should be stored undiluted at 4°C. Do not freeze.

Target Details for CD51/CD61

Target: CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Alternative Name: CD51/CD61

Background: The 23C6 monoclonal antibody specifically reacts with the human CD51/61 Molecule, known as the integrin alpha v Beta 3 complex or vitronectin receptor. The complex binds to other ligands such as CD29, fibrinogen, fibrinectin, vWf, laminin, and thrombospondin. It is expressed by endothelial cells, osteoclasts, melanoma cells, and at low levels on platelets and macrophages. The 23C6 antibody is reported to be able to block the receptors ability to form interactions with some of its ligands.

Gene ID: 3685, 3690

UniProt: P06756, P05106