The PE-conjugated Mouse Monoclonal anti-P-Selectin antibody (Clone AK-4) (ABIN2567887) specifically detects P-Selectin in FACS.
The antibody is reactive with Human samples.
The AK-4 monoclonal antibody specifically reacts with human CD62P (P-Selectin), a 140 kDA type I transmembrane glycoprotein also known as platelet activation-dependent granule membrane protein (PADGEM).
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target
P-Selectin (SELP)
(Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
Alternative Name
CD62P
Background
The AK-4 monoclonal antibody specifically reacts with human CD62P (P-Selectin), a 140 kDA type I transmembrane glycoprotein also known as platelet activation-dependent granule membrane protein (PADGEM). Upon activation it is quickly transported to the plasma membrane from the alpha-granules of platelets and WEibel-Palade bodies of endothelial cells. It is essential to the functions of cell adhesion during inflammatory reactions and in the interaction of platelets with monocytes and neutrophils.