CD8B antibody

Catalog No. ABIN2568041

This Mouse Monoclonal antibody specifically detects CD8B in FACS and Func. It exhibits reactivity toward Rat.

Quick Overview for CD8B antibody (ABIN2568041)

Target: CD8B (CD8b Molecule (CD8B))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD8B antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: 341

Product Details anti-CD8B Antibody

Specificity: The 341 monoclonal antibody specifically reacts with the beta chain of the Rat CD8 Molecule.

Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Storage: 4 °C

Storage Comment: The product should be stored undiluted at 4°C. Do not freeze.

Target Details for CD8B

Target: CD8B (CD8b Molecule (CD8B))

Alternative Name: CD8b

Background: The 341 monoclonal antibody specifically reacts with the beta chain of the Rat CD8 Molecule. The alpha and beta chains of the CD8 Molecule form a heterodimer common on most thymocytes. The CD8 positive T cells of athymic rats and most NK cells express a homodimer composed solely of CD8a. It is reported that macrophages express CD8 alpha and beta chains for signal transduction. CD8 is an antigen co-receptor that interacts with MHC class I molecules on antigen-presenting cells.

Gene ID: 24931

UniProt: P05541

Pathways: TCR Signaling