NOTCH3 antibody (APC)

Catalog No. ABIN2568400

This anti-NOTCH3 antibody is a Hamster Monoclonal antibody detecting NOTCH3 in FACS. Suitable for Mouse.

Quick Overview for NOTCH3 antibody (APC) (ABIN2568400)

Target: NOTCH3 (Notch 3 (NOTCH3))

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This NOTCH3 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: HMN3-133

Product Details anti-NOTCH3 Antibody (APC)

Specificity: The HMN3-133 monoclonal antibody specifically reacts with mouse Notch3, a single-pass transmembrane protein.

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Storage: 4 °C

Storage Comment: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Target Details for NOTCH3

Target: NOTCH3 (Notch 3 (NOTCH3))

Alternative Name: Notch3

Background: The HMN3-133 monoclonal antibody specifically reacts with mouse Notch3, a single-pass transmembrane protein. After binding with its ligand, Notch3 receptor undergoes cleavage resulting in a Notch intracellular domain (NICD) molecule that eventually activates transcription in the nucleus. It is expressed on Treg cells and adult smooth muscle arterial cells.

Gene ID: 18131

UniProt: Q61982

Pathways: Notch Signaling