TAL1 antibody (pSer122)

Catalog No. ABIN2568468

The Rabbit Polyclonal anti-TAL1 antibody is suitable to detect TAL1 in samples from Human and Rat. It has been validated for WB.

Quick Overview for TAL1 antibody (pSer122) (ABIN2568468)

Target: TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TAL1 Antibody

Binding Specificity: pSer122

Specificity: The antibody detects endogenous levels of TAL-1 only when phosphorylated at serine 122.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: TAL-1 (phospho Ser122) antibody was raised against a peptide sequence around phosphorylation site of Serine 122 (Q-L-S (p)-P-P) derived from Human TAL-1.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for TAL1

Target: TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

Alternative Name: TAL-1

Background: TAL-1 is a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.

Molecular Weight: 45 kDa

Gene ID: 6886

NCBI Accession: NP_001274276

UniProt: P17542

Pathways: Stem Cell Maintenance