LAG3 antibody (AA 70-99) (Atto 488)

Catalog No. ABIN2612231

This Mouse Monoclonal antibody specifically detects LAG3 in WB, IHC, IP, ICC, FACS, Func and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for LAG3 antibody (AA 70-99) (Atto 488) (ABIN2612231)

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LAG3 antibody is conjugated to Atto 488

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 17B4

Product Details anti-LAG3 Antibody (Atto 488)

Binding Specificity: AA 70-99

Specificity: Recognizes the 30 aa extra-loop of the first N-terminal D1 domain of human LAG-3.

Purification: Protein A purified from tissue culture supernatant

Immunogen: Synthetic peptide corresponding to 30 aa (GPPAAAPGHPLAPGPHPAAPSSWGPRPRRY) from the first N-terminal D1 domain of human LAG-3 (lymphocyte activation gene-3). Percent identity by BLAST analysis: Human (100%), Gorilla (93%), Gibbon (90%), Monkey (83%).

Type of Immunogen: Synthetic peptide

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:100), Func, ICC, IHC, IHC-Fr, IP, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry - 1:100.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

Target Details for LAG3

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Alternative Name: LAG3

Background: Name/Gene ID: LAG3

Synonyms: LAG3, CD223 antigen, LAG-3, Protein FDC, CD223, FDC, Lymphocyte-activation gene 3

Gene ID: 3902

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints