LAG3 antibody (AA 70-99)

Catalog No. ABIN2624682

The Mouse Monoclonal anti-LAG3 antibody has been validated for ICC and Func. It is suitable to detect LAG3 in samples from Human.

Quick Overview for LAG3 antibody (AA 70-99) (ABIN2624682)

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LAG3 antibody is un-conjugated

Application: Immunocytochemistry (ICC), Functional Studies (Func)

Clone: 17B4

Product Details anti-LAG3 Antibody

Binding Specificity: AA 70-99

Specificity: Recognizes the 30 aa extra-loop of the first N-terminal D1 domain of human LAG-3.

Purification: Protein A purified from tissue culture supernatant

Immunogen: Synthetic peptide corresponding to 30 aa (GPPAAAPGHPLAPGPHPAAPSSWGPRPRRY) from the first N-terminal D1 domain of human LAG-3 (lymphocyte activation gene-3). Percent identity by BLAST analysis: Human (100%), Gorilla (93%), Gibbon (90%), Monkey (83%).

Type of Immunogen: Synthetic peptide

Isotype: IgG1

Application Details

Application Notes: Approved: Func, ICC

Usage: Functional Application - Inhibition. Immunohistochemistry - Frozen sections (1:150. Immunoprecipitation - 10 μg/mL. Western Blot - 5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for LAG3

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Alternative Name: LAG3

Background: Name/Gene ID: LAG3

Synonyms: LAG3, CD223 antigen, LAG-3, Protein FDC, CD223, FDC, Lymphocyte-activation gene 3

Gene ID: 3902

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints