MAP3K8 antibody (pThr290)

Catalog No. ABIN2625110

This Rabbit Polyclonal antibody specifically detects MAP3K8 in WB, IHC, IHC (p), IF and ICC. It exhibits reactivity toward Human, Rat, Mouse, Cow and Monkey.

Quick Overview for MAP3K8 antibody (pThr290) (ABIN2625110)

Target: MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

Reactivity: Human, Rat, Mouse, Cow, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-MAP3K8 Antibody

Binding Specificity: pThr290

Specificity: Recognizes endogenous levels of TPL2 (pT290) protein.

Purification: Immunoaffinity purified

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the central region of human TPL2 (pT290).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: ICC (1:100 - 1:500), IF, IHC, IHC-P (1:100 - 1:200), WB (1:500 - 1:1000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.3, 0.01 % sodium azide, 30 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to avoid freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot to avoid freeze/thaw cycles.

Target Details for MAP3K8

Target: MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

Alternative Name: MAP3K8 / TPL2

Background: Name/Gene ID: MAP3K8
Subfamily: MAP3K
Family: Protein Kinase

Synonyms: MAP3K8, C-COT, Cancer Osaka thyroid oncogene, COT, Ewing sarcoma transformant, EST, MEKK8, Proto-oncogene c-Cot, TPL2, Tumor progression locus 2, Protein kinase cot, Tpl-2, ESTF

Gene ID: 1326

Pathways: PI3K-Akt Signaling, TCR Signaling