NR1H3 antibody (AA 371-385)
Quick Overview for NR1H3 antibody (AA 371-385) (ABIN2626274)
Target
See all NR1H3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 371-385
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Specificity
- Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals.
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Purification
- Immunogen affinity purified
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Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human LXR alpha(371-385aa NVQDQLQVERLQHTY), identical to the related rat and mouse sequences.
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Distilled water
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Concentration
- Lot specific
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Buffer
- Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.
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Preservative
- Sodium azide, Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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Handling Advice
- Avoid freeze-thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
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- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
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Alternative Name
- NR1H3 / LXR alpha
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Background
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Name/Gene ID: NR1H3
Subfamily: NR1 Thyroid hormone-like
Family: NHR
Synonyms: NR1H3, Liver X receptor alpha, LXRA, LXR-a, Oxysterols receptor LXR-alpha, LXR alpha, Lxralpha, RLD-1 -
Gene ID
- 10062
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
Target
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