RIPK3 antibody (AA 60-76)

Catalog No. ABIN2627666

This Rabbit Polyclonal antibody specifically detects RIPK3 in WB. It exhibits reactivity toward Human and Monkey.

Quick Overview for RIPK3 antibody (AA 60-76) (ABIN2627666)

Target: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIPK3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RIPK3 Antibody

Binding Specificity: AA 60-76

Specificity: Highly expressed in the pancreas. Detected at lower levels in heart, placenta, lung and kidney. Isoform 3 is significantly increased in colon and lung cancers. .

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human RIP3(60-76aa EVKAMASLDNEFVLRLE).

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.

Target Details for RIPK3

Target: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Alternative Name: RIPK3 / RIP3

Background: Name/Gene ID: RIPK3
Subfamily: RIP
Family: Protein Kinase

Synonyms: RIPK3, Receptor interacting protein 3, RIP-like protein kinase 3, RIP3, RIP-3, Receptor-interacting protein 3

Gene ID: 11035

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades