SNCA antibody
Quick Overview for SNCA antibody (ABIN2628576)
Target
See all SNCA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Recognizes the nitrated/oxidized and non-nitrated forms of human a-Synuclein protein. Cross-reactivity with b- and g-synucleins has not been observed in testing with bacterially-expressed and purified recombinant proteins. Species sequence homology: Mouse and rat: 95 % .
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Purification
- Protein A purified
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Immunogen
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Recombinant full-length oxidized human alpha-Synuclein.
Type of Immunogen: Recombinant protein -
Isotype
- IgG1
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Application Notes
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Approved: ELISA (0.1 - 1 μg/mL), ICC, IF, IHC, IHC-P (1 - 5 μg/mL), WB (1 - 3 μg/mL)
Usage: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Immunofluorescence (IC): 1-5 μg/mL mouse. ELISA: 0.1-1.0 μg/mL immunogen. Western Blot: 1-3 μg/mL Band at ~18kD. Immunohistochemistry (Paraffin): 1-5 μg human. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- SNCA (Synuclein, alpha (SNCA))
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Alternative Name
- SNCA / alpha-Synuclein
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Background
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Name/Gene ID: SNCA
Synonyms: SNCA, Alpha-synuclein, PARK4, PD1, Synuclein alpha-140, NACP, PARK1 -
Gene ID
- 6622
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UniProt
- P37840
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Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
Target
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