CRP antibody

Catalog No. ABIN263927

The Mouse Monoclonal anti-CRP antibody has been validated for EIA and ELISA (Detection). It is suitable to detect CRP in samples from Human.

Quick Overview for CRP antibody (ABIN263927)

Target: CRP (C-Reactive Protein (CRP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CRP antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), ELISA (Detection)

Clone: C7

Product Details anti-CRP Antibody

Specificity: The antibody C7 recognizes CRP, an 117 kDa acute phase protein. It recognizes antigen both in the presence and in the absence (samples containing EDTA) of Ca2+.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Synonyms: PTX1, C Reactive Protein, Pentraxin-related

Purification: Affinity Chromatography on Protein A

Immunogen: Purified human CRP

Isotype: IgG1

Application Details

Application Notes: ELISA: The clone C7 has been tested as the detection antibody in a Sandwich ELISA foranalysis of C-Reactive Protein in combination with the clone C5 (ABIN492603).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CRP

Target: CRP (C-Reactive Protein (CRP))

Background: The C-reactive protein (CRP) is a cyclic pentameric pentraxin family acute phase protein compound of five identical noncovalently bound nonglycosylated subunits (each subunit 24 kDa, physiologic CRP molecule 117,5 kDa). CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes occuring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.) and is also believed to play an important role in innate immunity. Patients with elevated basal levels of CRP are at increased risk for hypertension and cardiovascular disease.Synonyms: C Reactive Protein, PTX1, Pentraxin-related

Gene ID: 1401

UniProt: P02741

Pathways: Carbohydrate Homeostasis