DNA Adenine Methylase antibody
Quick Overview for DNA Adenine Methylase antibody (ABIN264462)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Gram Negative Bacteria.
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Characteristics
- Synonyms: DAM, Deoxyadenosyl-methyltransferase, DNA adenine methyltransferase
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Purification
- Purified
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Immunogen
- Recombinant DNA Adenine Methylase protein.
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Isotype
- IgG1
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Application Notes
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Western blot (5-10 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.08 % Sodium Azide as preservative.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. -
Expiry Date
- 12 months
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- DNA Adenine Methylase
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Background
- DNA adenine methylase (DAM) is an enzyme that methylates adenine residues in the 4-base pair DNA sequence, GATC. This methylation reaction has been shown to be crucial in a variety of cellular processes in bacteria. These include (i) the control of initiation of DNA replication (GATC occurs 11 times in the highly conserved bacterial origin of replication sequence), (ii) methyl-directed mismatch repair, (iii) control of transposition of certain transposable DNA elements, and (iv) control of gene expression. With regard to gene expression, the recent report by Heithoff et al. (Science, 284:967-970, 1999) showed that the deletion of the DAM gene rendered Salmonella typhimurium totally avirulent.Synonyms: DAM, DNA adenine methyltransferase, Deoxyadenosyl-methyltransferase
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Gene ID
- 947893
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UniProt
- P0AEE8
Target
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