DNA Adenine Methylase antibody
The Mouse Monoclonal anti-DNA Adenine Methylase antibody (Clone RB1) (ABIN306930) specifically detects DNA Adenine Methylase in WB.
The antibody is reactive with Gram Negative Bacteria samples.
Catalog No. ABIN306930
$368.50
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
Quick Overview for DNA Adenine Methylase antibody (ABIN306930)
Target
DNA Adenine Methylase
Reactivity
Gram Negative Bacteria
Host
Mouse
Clonality
Monoclonal
Conjugate
Un-conjugated
Application
Western Blotting (WB)
Clone
RB1
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Isotype
- IgG1
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Application Notes
- Antibody can be used for Western blotting (5-10 ug/ml). Other applications not yet evaluated.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/ml
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Storage
- -20 °C
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- DNA Adenine Methylase
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Background
- DNA adenine methylase (DAM) is an enzyme that methylates adenine residues in the 4-base pair DNA sequence, GATC. This methylation reaction has been shown to be crucial in a variety of cellular processes in bacteria. These include (i) the control of initiation of DNA replication (GATC occurs 11 times in the highly conserved bacterial origin of replication sequence), (ii) methyl-directed mismatch repair, (iii) control of transposition of certain transposable DNA elements, and (iv) control of gene expression. With regard to gene expression, the recent report by Heithoff et al. (Science, 284:967-970, 1999) showed that the deletion of the DAM gene rendered Salmonella typhimurium totally avirulent. Synonyms: DAM.
Target
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