MMP3 antibody (C-Term)

Catalog No. ABIN264506

Product Details anti-MMP3 Antibody

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Binding Specificity: C-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MMP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Matrix Metalloproteinase 3. Other species not tested.

Characteristics: Synonyms: Stromelysin-1, SL-1, Matrix metalloproteinase-3, Transin-1, MMP3, STMY1

Purification: Purified

Immunogen: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with asynthetic peptide derived from the Cterminus of the human MMP3 protein and mousemyeloma Ag8563 cells.

Clone: 1B4

Isotype: IgG1

Application Details

Application Notes: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections: 1 - 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS, 0.08 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for MMP3

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Alternative Name: MMP-3 (MMP3 Products)

Synonyms: CHDS6 antibody, MMP-3 antibody, SL-1 antibody, STMY antibody, STMY1 antibody, STR1 antibody, SLN-1 antibody, SLN1 antibody, STR-1 antibody, Stmy1 antibody, Str1 antibody, MMP10 antibody, chds6 antibody, mmp-3 antibody, mmp13 antibody, mmp3 antibody, sl-1 antibody, stmy antibody, stmy1 antibody, str1 antibody, matrix metallopeptidase 3 antibody, matrix metallopeptidase 3 (stromelysin 1, progelatinase) antibody, matrix metallopeptidase 3 L homeolog antibody, MMP3 antibody, Mmp3 antibody, mmp3.L antibody

Background: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including Collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.Synonyms: MMP3, Matrix metalloproteinase-3, SL-1, STMY1, Stromelysin-1, Transin-1

Molecular Weight: 50 kDa (Proenzyme)

Gene ID: 4314

UniProt: P08254