Clostridium Botulinum Type E Toxoid antibody
Quick Overview for Clostridium Botulinum Type E Toxoid antibody (ABIN264552)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Purification
- Protein G Sepharose chromatography
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Immunogen
- Type E Neurotoxin and complexing Proteins
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Application Notes
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Dot Blot. ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.3mg/mL (OD280/OD260)
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Buffer
- 1X PBS, pH 7.2 containing 20 % glycerol
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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- Clostridium Botulinum Type E Toxoid (BoNT-E) (Botulinum Neurotoxin Type E (BoNT-E))
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Alternative Name
- Botulinum Neurotoxin Type E
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Target Type
- Bacteria
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Background
- Clostridium botulinum E Toxoid acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase. It has a non-toxic component which is necessary to maintain toxicity.Synonyms: BoNT/E, Bontoxilysin-E, Clostridium Botulinum Toxin E
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Gene ID
- 1491
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UniProt
- Q00496
Target
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