CGA antibody
Quick Overview for CGA antibody (ABIN264631)
Target
See all CGA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- This antibody reacts with alpha chains on Thyroid Stimulating Hormone (TSH), Chorionic Gonadotropin (hCG), Luteinizing Hormone (LH), and Follicle Stimulating Hormone (FSH).
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Purification
- Immunoaffinity purified
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Purity
- > 98 % pure (PAGE)
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Immunogen
- Alpha-hCG
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Application Notes
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This antibody pairs with Monoclonal anti-beta hCG (Catalog ABIN263803) in the hCGsandwich immunoassay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 6.16mg/mL (OD280nm, E0.1% = 1.3)
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Buffer
- 0.1 M Potassium Phosphate buffer, 0.85 % NaCl, pH 7.8 containing 0.05 % Sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- DO NOT FREEZE! Slight precipitation may occur. If necessary, re-filter or centrifuge at 3,500 rpm for 30 minutes to remove the tiny precipitate.
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Storage
- 4 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C.
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- CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))
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Alternative Name
- Glycoprotein Hormones alpha Chain
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Background
- The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family.Synonyms: Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, FSH-alpha, Follicle-stimulating hormone alpha chain, Follitropin alpha chain, LH alpha, LSH-alpha, Luteinizing hormone alpha chain, Lutropin alpha chain, TSH-alpha, Thyroid-stimulating hormone alpha chain, Thyrotropin alpha chain, hCG-alpha
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Gene ID
- 1081
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NCBI Accession
- NP_000726
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UniProt
- P01215
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Pathways
- Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport, Peptide Hormone Metabolism
Target
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