TNNI3 antibody (AA 69-86)
Quick Overview for TNNI3 antibody (AA 69-86) (ABIN264705)
Target
See all TNNI3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 69-86
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Specificity
- This antibody is specific for Human Cardiac Troponin I. Recognizes epitopes located in the 69-86 region of Troponin I. Cross reactivity with Human skeletal Troponin I is 1 % by ELISA.
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Purification
- Affinity purified with Solid Phase Human Cardiac Troponin I, region 69-86
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Immunogen
- Highly purified Human Cardiac Troponin I
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Application Notes
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Immunoassay. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 6.54 mg/mL (OD280nm, E1% = 13)
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Buffer
- 10 mM Sodium Phosphate, 0.85 % (w/v) Sodium Chloride, pH 7.2, 0.05 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- DO NOT FREEZE!
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Storage
- 4 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C.
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- TNNI3 (Cardiac Troponin I (TNNI3))
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Alternative Name
- Cardiac Troponin I
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Background
- Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.Synonyms: TNNC1, TNNI3
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Gene ID
- 7137
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NCBI Accession
- NP_000354
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UniProt
- P19429
Target
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