PRSS1 antibody

Catalog No. ABIN264781

This Rabbit Polyclonal antibody specifically detects PRSS1 in WB, EIA and ID. It exhibits reactivity toward Human.

Quick Overview for PRSS1 antibody (ABIN264781)

Target: PRSS1 (Protease, serine, 1 (Trypsin 1) (PRSS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRSS1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunodiffusion (ID)

Product Details anti-PRSS1 Antibody

Specificity: This antibody reacts to Cationic Trypsin.

Purification: Ammonium Sulfate Precipitation and DEAE-Sephacel Ion Exchange Chromatography

Immunogen: Human Cationic Trypsin.

Application Details

Application Notes: Indirect ELISA: 1/512. Western blot: 1/2,000 reacts to 0.3 μg antigen. IEP: Single arc against antigen and human pancreatic extract.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.467 mg/mL

Buffer: PBS, pH 7.4 containing 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for PRSS1

Target: PRSS1 (Protease, serine, 1 (Trypsin 1) (PRSS1))

Alternative Name: Trypsin-1 / PRSS1

Background: Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screen for and diagnose Cystic Fibrosis.Synonyms: Beta-trypsin, Cationic trypsinogen, Serine protease 1, TRP1, TRY1, TRYP1, Trypsin I

Gene ID: 5644

NCBI Accession: NP_002760

UniProt: P07477