EBV antibody

Catalog No. ABIN264914

Product Details anti-EBV Antibody

Target: EBV (Epstein-Barr Virus (EBV))

Reactivity: Epstein-Barr Virus (EBV)

Host: Sheep

Clonality: Polyclonal

Conjugate: This EBV antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Application Details

Application Notes: Immunoblotting. Immunoprecipitates EBNA-3C when used at a dilution of1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS, 0.08 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

References for anti-EBV antibody (ABIN264914)

Cuchillo-Ibáñez, Balmaceda, Botella-López, Rabano, Avila, Sáez-Valero: "Beta-amyloid impairs reelin signaling." in: PLoS ONE, Vol. 8, Issue 8, pp. e72297, (2014) (PubMed).

Hideyama, Teramoto, Hachiga, Yamashita, Kwak: "Co-occurrence of TDP-43 mislocalization with reduced activity of an RNA editing enzyme, ADAR2, in aged mouse motor neurons." in: PLoS ONE, Vol. 7, Issue 8, pp. e43469, (2013) (PubMed).

Jiménez-Ramírez, Brooks, Forshell, Yakimchuk, Zhao, Fulgham, Sample: "Epstein-Barr virus EBNA-3C is targeted to and regulates expression from the bidirectional LMP-1/2B promoter." in: Journal of virology, Vol. 80, Issue 22, pp. 11200-8, (2006) (PubMed).

Yuan, Cahir-McFarland, Zhao, Kieff: "Virus and cell RNAs expressed during Epstein-Barr virus replication." in: Journal of virology, Vol. 80, Issue 5, pp. 2548-65, (2006) (PubMed).

Hong, Gulley, Feng, Delecluse, Holley-Guthrie, Kenney: "Epstein-Barr virus lytic infection contributes to lymphoproliferative disease in a SCID mouse model." in: Journal of virology, Vol. 79, Issue 22, pp. 13993-4003, (2005) (PubMed).

Maruo, Johannsen, Illanes, Cooper, Kieff: "Epstein-Barr Virus nuclear protein EBNA3A is critical for maintaining lymphoblastoid cell line growth." in: Journal of virology, Vol. 77, Issue 19, pp. 10437-47, (2003) (PubMed).

ONions, Allday: "Epstein-Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2." in: Oncogene, Vol. 22, Issue 46, pp. 7181-91, (2003) (PubMed).

Rosendorff, Illanes, David, Lin, Kieff, Johannsen: "EBNA3C coactivation with EBNA2 requires a SUMO homology domain." in: Journal of virology, Vol. 78, Issue 1, pp. 367-77, (2003) (PubMed).

Gordadze, Peng, Tan, Liu, Sutton, Kempkes, Bornkamm, Ling: "Notch1IC partially replaces EBNA2 function in B cells immortalized by Epstein-Barr virus." in: Journal of virology, Vol. 75, Issue 13, pp. 5899-912, (2001) (PubMed).

Labbé, Letamendia, Attisano: "Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 15, pp. 8358-63, (2000) (PubMed).

Target Details for EBV

Target: EBV (Epstein-Barr Virus (EBV))

Alternative Name: Epstein Barr Virus / EBV (EBV Products)

Target Type: Virus

Background: EBNA-3C is a latent viral nuclear protein expressed in EBV transformed lymphoblastic cell lines and is essential for EBV mediated transformation of these cell lines. This viral nuclear protein is essential for EBV mediated positive immunoblastic lymphomas, and functions as a transcription factor.Synonyms: HHV-4, HHV4