S100A7
Reactivity: Human
IHC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Western blotting. Immunohistochemistry of paraffin and formalin fixed tissues. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline with 0.08 % Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Psoriasin antibody detects psoriasin by both western blot and on formalin and paraffin fixed tissue sections. The staining on tissue sections is both nuclear and cytoplasmic. Although its expression in breast cancer is downregulated (in both preinvasive and invasive cancers) when its expression is maintained in breast cancer the expression of psoriasin is correlated with estrogen receptor negativity and node positivity and therefore with poor prognostic features. Further it is correlated with the degree of inflammation inthe tumor which is consistent with its being a chemotactic factor.Synonyms: PSOR1, S100 calcium-binding protein A7, S100-A7, S100A7C