ADAR antibody (AA 1116-1176)

Catalog No. ABIN264971

The Sheep Polyclonal anti-ADAR antibody is suitable to detect ADAR in samples from Rat. It has been validated for WB.

Quick Overview for ADAR antibody (AA 1116-1176) (ABIN264971)

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Reactivity: Rat

Host: Sheep

Clonality: Polyclonal

Conjugate: This ADAR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADAR Antibody

Binding Specificity: AA 1116-1176

Specificity: This antibody reacts to DRADA.

Purification: Purified

Immunogen: GST fusion protein containing amino acid 1116-1176 of the rat DRADA coding sequence. The fusion protein was constructed in the pGEX-KG vector by inserting a fragment corresponding to nucleotides +3346 through +3525 of DRADA at the XbaI and XhoI sites in the vector.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for ADAR

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Alternative Name: ADAR1 / DRADA

Background: Double stranded RNA specific adenosine deaminase 1 (ADAR1 or DRADA) is an enzyme involved in the editing of mammalian messenger RNAs by the site specific conversion of adenosine to inosine. ADAR 1 is thought to play a role in the editing of transcripts encoding non-NMDA glutamate receptor subunits, the 2C subtype of serotonin receptor, as well as hepatitis delta virus antigen.Synonyms: 136 kDa double-stranded RNA-binding protein, DSRAD, Double-stranded RNA-specific adenosine deaminase, G1P1, IFI4, Interferon-inducible protein 4, K88DSRBP, P136

Gene ID: 81635

NCBI Accession: NP_112268

UniProt: P55266

Pathways: Protein targeting to Nucleus