RED1 antibody (AA 6-66)

Catalog No. ABIN264972

Product Details anti-RED1 Antibody

Target: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Binding Specificity: AA 6-66

Reactivity: Rat

Host: Sheep

Clonality: Polyclonal

Conjugate: This RED1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificity: This antibody recognizes ADAR2 (Adenosine Deaminase Acting on RNA 2).

Purification: Purified

Immunogen: GST fusion protein containing aa 6-66 of the rat RED1 coding sequence

Isotype: IgG

Application Details

Application Notes: Western Blot: 1: 1000. POSITIVE CONTROL: Rat Brain.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

References for anti-RED1 antibody (ABIN264972)

Yamashita, Chai, Teramoto, Tsuji, Shimazaki, Muramatsu, Kwak: "Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons." in: EMBO molecular medicine, Vol. 5, Issue 11, pp. 1710-9, (2013) (PubMed).

Dorsam, Graeler, Seroogy, Kong, Voice, Goetzl: "Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 7, pp. 3500-7, (2003) (PubMed).

Target Details for RED1

Target: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Alternative Name: ADARB1 / ADAR2 (ADARB1 Products)

Synonyms: ADARB1 antibody, RED1 antibody, ADAR2 antibody, DRABA2 antibody, DRADA2 antibody, 1700057H01Rik antibody, AW124433 antibody, AW558573 antibody, Adar2 antibody, BB220382 antibody, D10Bwg0447e antibody, Red1 antibody, adar2 antibody, adarb1 antibody, red1 antibody, adenosine deaminase, RNA specific B1 antibody, adenosine deaminase, RNA-specific, B1 antibody, adenosine deaminase, RNA-specific, B1 L homeolog antibody, adenosine deaminase, RNA-specific, B1a antibody, ADARB1 antibody, adarb1 antibody, adarb1.L antibody, Adarb1 antibody, adarb1a antibody

Background: RED 1 also called ADAR2 is involved in the editing of the messenger RNAs for glutamate receptor (GluR) subunits by siteselective adenosine deamination. It edits both the GluR-B Q/R and R/G sites efficiently but converts the adenosine in hotspot1 much less efficiently.Synonyms: DRADA2, Double-stranded RNA-specific editase 1, RED1, RNA-editing deaminase 1, RNA-editing enzyme 1, dsRNA adenosine deaminase

Molecular Weight: 80.7 kDa

Gene ID: 25367

NCBI Accession: NP_001104525

UniProt: P51400