Adiponectin Receptor 2 antibody
Quick Overview for Adiponectin Receptor 2 antibody (ABIN265112)
Target
See all Adiponectin Receptor 2 (ADIPOR2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- This antibody reacts to Adiponectin Receptor 2. Cross reacts with Human ADR1.
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Purification
- Purified
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Immunogen
- Synthetic peptide derived from human adiponectin receptor 2 protein.
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Application Notes
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ELISA. Western Blot: 5 - 10 μg/mL. Positive Control: Colon, Hippocampus, and Trachea.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- Phosphate buffered saline with 0.08 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- Adiponectin Receptor 2 (ADIPOR2)
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Alternative Name
- Adiponectin Receptor 2
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Background
- ADR2 functions as a receptor for globular and full-length adiponectin (APM1), which is an essential hormone secreted by adipocytes that acts as an antidiabetic. ADR2 is also probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. ADR2 mediates an increase in AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin and has some intermediate-affinity receptor activity for both globular and full-length adiponectin. ADR2 may form homo and heteromultimers.Synonyms: ADIPOR2, PAQR2, Progestin and adipoQ receptor family member II
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Gene ID
- 79602
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NCBI Accession
- NP_078827
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UniProt
- Q86V24
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Pathways
- AMPK Signaling
Target
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