Ceremide Kinase antibody
Quick Overview for Ceremide Kinase antibody (ABIN265118)
Target
Reactivity
Host
Clonality
Application
-
-
Purification
- Purified
-
Immunogen
- Recombinant full-length human ceramide kinase protein
-
-
-
Application Notes
-
ELISA. Western Blot: 1 - 10 μg/mL. Positive Control: High level expression in heart, brain, skeletal muscle, kidney and liver.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Buffer
- Phosphate buffered saline with 0.08 % sodium azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- Avoid repeated freezing and thawing.
-
Storage
- -20 °C
-
Storage Comment
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
-
-
- Ceremide Kinase
-
Background
- Sphingolipids and their metabolic products, including ceramide, sphingosine, and sphingosine-1-phosphate (S1P),1 are important signaling molecules in many biological processes. Ceramide has been is one of the key elements regulating apoptotic responses. Ceramide has been reported as a regulator of several protein kinases and phosphatases, including ceramide-activated protein kinase, protein phosphatase, and protein kinase C. Sphingosine, a metabolite of ceramide, might also play a role in mitochondriamediated apoptosis. Sphingosine inhibits several protein kinases, including protein kinase C and Ca2 -calmodulin-dependent kinase II. S1P regulates many biological processes, including mitogenesis, differentiation, migration, and suppression of apoptosis.Synonyms: Acylsphingosine kinase, LK4, Lipid kinase 4, hCERK
Target
-