Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) antibody

Catalog No. ABIN265281

The Rabbit Polyclonal anti-Purinergic Receptor P2Y, G-Protein Coupled, 13 antibody (ABIN265281) specifically detects Purinergic Receptor P2Y, G-Protein Coupled, 13 in WB. The antibody is reactive with Human samples.

Quick Overview for Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) antibody (ABIN265281)

Target: Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Specificity: This antibody detects P2Y13.

Purification: Purified

Immunogen: Synthetic peptide derived from human GPCR94

Application Details

Application Notes: Western blot (1-5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Target Details

Target: Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13)

Alternative Name: P2Y13 / P2YR13

Background: Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined. Stimulation by ADP in stably transfected CHO cells resulted in inhibition of adenylyl cyclase and the phosphorylation of the MAP kinases MAPK3 and MAPK1 in a pertussis toxin-sensitive way. Inhibition of adenylyl cyclase and phosphorylation of the MAP kinases are transduction mechanisms that involve G(i) proteins.Synonyms: FKSG77, G-protein coupled receptor 86, G-protein coupled receptor 94, GPR86, GPR94, P2Y purinoceptor 13, Purinergic receptor

Gene ID: 53829

NCBI Accession: NP_795713

UniProt: Q9BPV8

Pathways: cAMP Metabolic Process