IL-10RA antibody (APC)

Catalog No. ABIN2657036

The APC-conjugated Rat Monoclonal anti-IL-10RA antibody (Clone 3F9) (ABIN2657036) specifically detects IL-10RA in WB. The antibody is reactive with Human samples.

Quick Overview for IL-10RA antibody (APC) (ABIN2657036)

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-10RA antibody is conjugated to APC

Application: Western Blotting (WB)

Clone: 3F9

Product Details anti-IL-10RA Antibody (APC)

Cross-Reactivity: Cynomolgus, Rhesus Monkey

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for IL-10RA

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Alternative Name: CD210

Background: CD210, also known as the IL-10 receptor, is a 90-110 kD protein expressed on T cells, B cells, NK cells, monocytes and macrophages. CD210 belongs to the class II cytokine receptor family which includes the IFN-γ receptor (CDw119), the IFN-α/β receptor (CD118) and tissue factor (CD142). The IL-10 receptor is involved in signal transduction by inducing phosphorylation of STAT1a and STAT3 and by inducing activation of Jak1 and Tyk.

Pathways: Growth Factor Binding