TUBB3 antibody (Alexa Fluor 488)

Catalog No. ABIN2657111

The Alexa Fluor 488-conjugated Mouse Monoclonal anti-TUBB3 antibody (Clone AA10) (ABIN2657111) specifically detects TUBB3 in ICFC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TUBB3 antibody (Alexa Fluor 488) (ABIN2657111)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This TUBB3 antibody is conjugated to Alexa Fluor 488

Application: Intracellular Flow Cytometry (ICFC)

Clone: AA10

Product Details anti-TUBB3 Antibody (Alexa Fluor 488)

Purification: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Alternative Name: Tubulin beta 3

Background: Tubulin is the main component of microtubules. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. Mutations in this gene cause congenital fibrosis of the type 3 extraocular muscles. Tubulin beta 3 (TUBB3) is also found in a wide range of tumors. Studies indicate that it is a predictive and prognostic marker in various tumors.

Pathways: Microtubule Dynamics, M Phase