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CCR5 antibody (Alexa Fluor 647)
CCR5
Reactivity: Mouse
Func, Neut
Host: Hamster
Monoclonal
HM-CCR5
Alexa Fluor 647
Product Details anti-CCR5 Antibody (Alexa Fluor 647)
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Target
See all CCR5 Antibodies
CCR5
(Chemokine (C-C Motif) Receptor 5 (CCR5))
Reactivity
All reactivities for CCR5 antibodies
Mouse
Host
All hosts for CCR5 antibodies
Hamster
Clonality
All clonalities for CCR5 antibodies
Monoclonal
Conjugate
All conjugates for CCR5 antibodies
This CCR5 antibody is conjugated to Alexa Fluor 647
Application
All applications for CCR5 antibodies
Functional Studies (Func), Neutralization (Neut)
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone
HM-CCR5
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C
Target Details for CCR5
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Target
CCR5
(Chemokine (C-C Motif) Receptor 5 (CCR5))
Alternative Name
CD195 (CCR5 Products )
Synonyms
CC-CKR-5 antibody, CCCKR5 antibody, CCR-5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody, IDDM22 antibody, Ckr5 antibody, Cmkbr5 antibody, CCR1-L antibody, GPCR antibody, CCR5 antibody, AM4-7 antibody, C-C motif chemokine receptor 5 (gene/pseudogene) antibody, chemokine (C-C motif) receptor 5 antibody, C-C motif chemokine receptor 5 antibody, CCR5 antibody, Ccr5 antibody
Background
CD195 is a 45 kD chemokine receptor also known as CCR5. CD195 is a seven transmembrane-spanning G protein-associated molecule expressed on macrophages, a T cell subset, and in the heart, liver, and spleen. CD195 regulates lymphocyte chemotaxis and transendothelial migration during inflammatory processes. CD195 interacts with several ligands including RANTES, MCP-1, MIP-1α, and MIP-1β.
Pathways
Cellular Response to Molecule of Bacterial Origin , cAMP Metabolic Process , Regulation of Cell Size
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