Integrin alpha 1 antibody (Alexa Fluor 647)

Catalog No. ABIN2657810

The Alexa Fluor 647-conjugated Mouse Monoclonal anti-Integrin alpha 1 antibody (Clone TS2-7) (ABIN2657810) specifically detects Integrin alpha 1 in WB, IP and ELISA (Capture). The antibody is reactive with Human samples.

Quick Overview for Integrin alpha 1 antibody (Alexa Fluor 647) (ABIN2657810)

Target: Integrin alpha 1 (ITGA1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin alpha 1 antibody is conjugated to Alexa Fluor 647

Application: Western Blotting (WB), Immunoprecipitation (IP), ELISA (Capture)

Clone: TS2-7

Product Details anti-Integrin alpha 1 Antibody (Alexa Fluor 647)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for Integrin alpha 1

Target: Integrin alpha 1 (ITGA1)

Alternative Name: CD49a

Background: CD49a is a 200 kD type I transmembrane glycoprotein also known as α1 integrin, VLA-1 α chain, or Integrin α1. It associates with CD29 (β1 integrin) to form VLA-1 complex, a collagen IV and alminin-1 receptor and that is expressed on activated T cells, monocytes, NK cells, smooth muscle cells, neuronal cells, fibroblasts, and mesenchymal cells.CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration, T cell proliferation, and cytokine production.

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex