NCR1 antibody (APC)

Catalog No. ABIN2658198

The APC-conjugated Rat Monoclonal anti-NCR1 antibody (Clone 29A1-4) (ABIN2658198) specifically detects NCR1 in ICFC. The antibody is reactive with Mouse samples.

Quick Overview for NCR1 antibody (APC) (ABIN2658198)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This NCR1 antibody is conjugated to APC

Application: Intracellular Flow Cytometry (ICFC)

Clone: 29A1-4

Product Details anti-NCR1 Antibody (APC)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Alternative Name: CD335

Background: CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NK-like T cells, it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.

Pathways: Regulation of Leukocyte Mediated Immunity