IL21 Receptor antibody (PE-Cy5)

Catalog No. ABIN2659037

The PE-Cy5-conjugated Rat Monoclonal anti-IL21 Receptor antibody (Clone 4A9) (ABIN2659037) specifically detects IL21 Receptor in IF. The antibody is reactive with Mouse samples.

Quick Overview for IL21 Receptor antibody (PE-Cy5) (ABIN2659037)

Target: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL21 Receptor antibody is conjugated to PE-Cy5

Application: Immunofluorescence (IF)

Clone: 4A9

Product Details anti-IL21 Receptor Antibody (PE-Cy5)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE/Cy5 under optimal conditions. The solution is free of unconjugated PE/Cy5 and unconjugated antibody.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for IL21 Receptor

Target: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Alternative Name: IL-21 Receptor

Background: The IL-21R is a member of the cytokine receptor family that closely resembles IL-2R beta and IL-4R alpha. IL-21R is expressed by all mature lymphocytes and up-regulated after B and/or T cell activation, with the highest expression by activated B cells. A functional IL-21R consists of the IL-21R subunit and the commone gamma-chaiin. Upon binding to IL-21, it activates Jak-1, Jak-3, STAT1, STAT3 and STAT 5 transduction pathway.

Pathways: JAK-STAT Signaling