IL-27 antibody (Biotin)

Catalog No. ABIN2660777

This Rat Monoclonal antibody specifically detects IL-27 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for IL-27 antibody (Biotin) (ABIN2660777)

Target: IL-27 (IL27) (Interleukin 27 (IL27))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-27 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: B02P6E6

Product Details anti-IL-27 Antibody (Biotin)

Purification: The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for IL-27

Target: IL-27 (IL27) (Interleukin 27 (IL27))

Alternative Name: IL-27

Background: IL-27, a heterodimer protein, belongs to the IL-12 cytokine family. IL-27 is composed of the Epstein-Barr virus-induced gene 3 (EBI-3), a 34 kD glycoprotein that is related to the p40 subunit of IL-12, and p28, a 28 kD glycoprotein that is related to the p35 subunit of IL-12 and p19 subunit of IL-23. IL-27 triggers expansion of antigen-specific naive CD4+ T cells, promotes polarization of Th1 cells, and inhibits the development of Th2 and Th17 cells. It is known that IL-27 is an early product of activated antigen-presenting cells (APCs). IL-27 plays an important role in regulating the activity of B and T lymphocytes.