IL-10RA antibody (Biotin)

Catalog No. ABIN2660993

The Biotin-conjugated Rat Monoclonal anti-IL-10RA antibody (Clone 1B1-3a) (ABIN2660993) specifically detects IL-10RA in FACS and CyTOF. The antibody is reactive with Mouse samples.

Quick Overview for IL-10RA antibody (Biotin) (ABIN2660993)

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-10RA antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Mass Cytometry (CyTOF)

Clone: 1B1-3a

Product Details anti-IL-10RA Antibody (Biotin)

Purification: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for IL-10RA

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Alternative Name: CD210

Background: CD210 is a 90-110 kD IL-10 receptor. It is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Ligand binding of CD210 induces Jak1 and Tyk, resulting in STAT1 and STAT3 activation. IL-10 receptor stimulation results in the inhibition of cytokine production and the costimulation of B cell proliferation and differentiation. The only known ligand for this receptor is IL-10.

Pathways: Growth Factor Binding