CD4 antibody (Biotin)

Catalog No. ABIN2661070

The Mouse Monoclonal anti-CD4 antibody has been validated for ICFC, ELISPOT (Detection) and ELISA (Detection). It is suitable to detect CD4 in samples from Human.

Quick Overview for CD4 antibody (Biotin) (ABIN2661070)

Target: CD4

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD4 antibody is conjugated to Biotin

Application: Intracellular Flow Cytometry (ICFC), ELISpot (Detection) (ELISPOT (Detection)), ELISA (Detection)

Clone: RPA-T4

Product Details anti-CD4 Antibody (Biotin)

Cross-Reactivity: Chimpanzee

Purification: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background: CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules, and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16.

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events