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IFNAR1 antibody (Biotin)
IFNAR1
Reactivity: Mouse
IHC, FACS
Host: Mouse
Monoclonal
MAR1-5A3
Biotin
Product Details anti-IFNAR1 Antibody (Biotin)
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Target
See all IFNAR1 Antibodies
IFNAR1
(Interferon alpha/beta Receptor 1 (IFNAR1))
Reactivity
All reactivities for IFNAR1 antibodies
Mouse
Host
All hosts for IFNAR1 antibodies
Mouse
Clonality
All clonalities for IFNAR1 antibodies
Monoclonal
Conjugate
All conjugates for IFNAR1 antibodies
This IFNAR1 antibody is conjugated to Biotin
Application
All applications for IFNAR1 antibodies
Immunohistochemistry (IHC), Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Clone
MAR1-5A3
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for IFNAR1
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Target
IFNAR1
(Interferon alpha/beta Receptor 1 (IFNAR1))
Alternative Name
IFNAR-1 (IFNAR1 Products )
Synonyms
ifnar1 antibody, IFNAR1 antibody, CD118 antibody, Ifar antibody, Ifnar antibody, Ifrc antibody, Infar antibody, AVP antibody, IFN-alpha-REC antibody, IFNAR antibody, IFNBR antibody, IFRC antibody, IFN-R-1 antibody, interferon alpha and beta receptor subunit 1 antibody, interferon-alpha/beta receptor alpha chain-like antibody, interferon (alpha and beta) receptor 1 antibody, interferon alpha/beta receptor 1 antibody, IFNAR1 antibody, ifnar1 antibody, Ifnar1 antibody, LOC609830 antibody
Background
IFNAR-1, the type I IFN receptor subunit 1, is coexpressed with IFNAR-2 on nearly all cells and make up the heterodimeric receptor complex that binds to all type I IFNs (IFN-α/β). Type I IFNs are a group of structurally and functionally related cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor, and autoimmune responses. Ligand binding to the IFN-α/β receptor complex leads to the tyrosine phosphorylation and activation of IFNAR-1-associated Tyk2 and IFNAR-2-associated Jak1 signal transductions.
Pathways
JAK-STAT Signaling , Hepatitis C
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