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IL-12/IL-23 p40 antibody (Biotin)

The Mouse Monoclonal anti-IL-12/IL-23 p40 antibody has been validated for FACS. It is suitable to detect IL-12/IL-23 p40 in samples from Human.
Catalog No. ABIN2661204

Quick Overview for IL-12/IL-23 p40 antibody (Biotin) (ABIN2661204)

Target

IL-12/IL-23 p40

Reactivity

  • 6
  • 3
  • 1
Human

Host

  • 6
  • 3
Mouse

Clonality

  • 9
Monoclonal

Conjugate

  • 5
  • 2
  • 1
  • 1
This IL-12/IL-23 p40 antibody is conjugated to Biotin

Application

  • 5
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  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Clone

C8-6
  • Cross-Reactivity (Details)

    IL-12/IL-23 p40 subunit (monomer, homodimer and heterodimer IL-12 p35/p40 or IL-23 p19/p40)

    Characteristics

    The C8.6 antibody reacts with human IL-12 p40 subunit of the IL-12 p70 heterodimer and IL-23 p40 subunit of the IL-23 p19/p40, as well as p40 monomer and homodimer. The C8.6 antibody has been reported to strongly inhibit different biological activities of IL-12, (e.g., IFN-gamma induction, mitogenic effects on PHA blasts, and enhancement of NK cell-mediated cytotoxicity). The C8.6 antibody can neutralize the bioactivity of natural or recombinant IL-12.

    Purification

    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

    Isotype

    IgG1 kappa
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    0.5 mg/mL

    Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Do not freeze.

    Storage

    4 °C

    Storage Comment

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target

    IL-12/IL-23 p40
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